Betahistine Hydrochloride‘s chemical name is 2 (2′ meihylaminoethyl) pyridine dihydrochloride. The tinnitus therapy with transmitter antagonists can influence a special form of tinnitus – the so called cochlear synaptic tinnitus. Most report tinnitus diminishing to a more manageable level without complete resolution. Although an antagonism between Betahistine and antihistamines could be expected on a theoretical basis, no such interactions have been reported. Stabilometric parameters in patients before and after betahistine therapy are outlined in Table 3. Since 2001, controlled trials suggest that ginkgo for tinnitus is not working (Drew et al, 2001).
In addition, betahistine has a powerful antagonistic effects at H3 receptors, and increases the levels of neurotransmitters released from the nerve endings. There is a case report of an interaction with ethanol and a compound containing pyrimethamine with dapsone and another of potentiation of betahistine with salbutamol. We don’t find this statistic much use as tinnitus is highly prevalent in otherwise normal persons. The greater the numerical expression, the worse the control of vertigo attacks after therapy. Most people with tinnitus are neither depressed nor seriously bothered by their tinnitus. If you forget to take a dose, do not worry, just remember to take the next dose when it is due.
Our balance is controlled in the inner ear and if there was a problem with it, walking would certainly make it worse to a sitting position, so I can understand why your doctor has prescribed betahistine. Pan T, Tyler RS, Ji H, Coelho C, Gogel SA. Differences Among Patients That Make Their Tinnitus Worse or Better. Betahistine Hydrochloride as a treatment is not always successful and surgery is sometimes required.
Betahistine – wikipedia, the free encyclopedia, Betahistine dihydrochloride (brand names veserc, serc, hiserk, betaserc) is an anti- vertigo drug. If you buy any medicines, check with a pharmacist that they are suitable to take with betahistine. These results are valid for patients with definite unilateral or bilateral Meniere’s disease who had at least two monthly vertigo attacks in the three months before enrolment and who would receive betahistine as first line treatment, irrespective of whether they had received betahistine before.
In another study of patients with BPPV the application of a Betahistine dihydrochloride two weeks after a physical treatment showed better results for restoring vestibular function compared to the only physical treatment group17. Oral betahistine was administered in two different doses: 8 mg three times daily and 16 mg three times daily, for 120-180 days (mean, 132 days). Conclusions: Betahistine does not significantly reduce tinnitus in Ménière’s patients treated for vestibular symptoms.
The patients who could use betahistine made up the study group, while the control group had those patients who could not use the drug for numerous reasons, including severe gastritis, ulcer, pregnancy, asthma and hypersensitivity to the drug. Due to a problem with our database we lost all post comments referring to Betahistine. Only the results after betahistine treatment with the higher dose were significantly different from the results obtained before therapy. Many people say their tinnitus is more active when they’re tired and stressed out.
However, if you have not there is\are no special diets or specific foods that you must exclude from your diet when taking the active ingredient Betahistine. Despite the above quotes, one prominent American tinnitus specialist says that gingko does no better in rigorous scientific studies than a placebo effect of 5%. I stopped making lifestyle sacrifices that seemed to have no positive affect on my tinnitus. It gives your ear something else to listen to and diverts your attention from the tinnitus.
Further long term randomised, placebo controlled trials with higher betahistine doses than examined in this trial could be considered to confirm or disprove our findings and explore the potential prophylactic capacities of betahistine for Meniere’s disease. Mahboubi H, Ziai K, Brunworth J, Djalilian HR.Accuracy of tinnitus pitch matching using a web-based protocol. Betahistine dihydrochloride is an orally administered, centrally acting histamine H1 receptor agonist with partial H3 antagonistic activity. Forty seven of these patients were treated with betahistine for vestibular symptoms.
Furthermore, we used pure tone audiometry to determine hearing loss (recorded in dB) during bone conduction for test conditions 250 Hz, 500 Hz, 1000 Hz, and 2000 Hz, and to determine the tinnitus intensity (in dB). Clinical intolerance to Betahistine may occur in bronchial asthma patients (see section 4.5 and 4.8) – These patients should therefore be monitored carefully during the treatment with betahistine. Nimodipine exerts not only an additional effect on the control of vertigo attacks and a further reduction of vestibulo-spinal impairment, but also a specific and positive action on tinnitus annoyance and sensorineural hearing loss.
The dose prescribed varies from person to person and you should follow the instructions given by your doctor. The salt restriction is intended for those who might have a subclinical form of Meniere’s Caffeine and similar substances increase tinnitus in a nonspecific fashion. As of now there is no effective medication that can completely treat Meniere’s disease.
On the other hand, the literature also mentions that tinnitus may be an adverse effect of antidepressant drugs, such as phenelzine, amitriptyline, protriptyline, doxepin, imipramine, fluoxetine, trazodone, bupropion, venlafaxine. The most common side effects of Betahistine may be: Feeling sick, indigestion, Headache, Skin itching and rash. Although betahistine is said to be well tolerated, in many people, it is possible to be allergic to the drug.
Apart from the usual side effects most all of us experience, on the face of it, with the information found, it would appear betahistine would not interact with antidepressants. Strupp et al. (5) have found that the number of attacks after 12 months was significantly lower in the high dosage group (48 mg tid, n=62) than in the low dosage group (16 mg tid, n=21, 24 mg, n=29) with betahistine dihydrochloride therapy. This works well for me and I would suggest it to anyone having trouble sleeping because of their tinnitus.